Actuality: Chronic heart failure (CHF) is a syndrome that develops as a complication of most cardiovascular diseases, which in particular can be one of the reasons for the transition of preasthenia to asthenia in elderly and senile individuals. Studies show a high prevalence of geriatric syndromes among elderly patients with chronic heart failure (CHF). It seems relevant to study the syndrome of senile asthenia (SA) in patients with decompensated CHF. Objective: to study the gender and age aspects of patients with CHF decompensation. To assess the relationship between FR and CHF decompensation. Materials and Methods: 107 patients aged 46-95 years with decompensated CHF functional class III-IV were included. 4 groups were formed: 1st - 29 people (53.9 ± 4.5 years), middle age (46-60 years); 2nd - 31 people (68.3 ± 5.0 years) elderly (61-74 years); 3rd - 40 people (81.5 ± 4.1 years) old age (75-89 years). 4th - 7 people (92.4 ± 1.4 years) of the age of centenarians (> 90 years). The patients underwent: examination, assessment of marital status, determination of BMI, brain natriuretic peptide (BNP), chest X-ray. Geriatric syndromes were assessed using a comprehensive geriatric assessment (CGE) using the Specialized Geriatric Examination program. Results: in the middle (n = 29) and elderly (n = 31) groups, there was a predominance of men (100% and 51.6%, respectively). The share of women in the old age group (n = 40) is 67.5%, in the long- liver group (n = 7) - 85.7%. There was a significant difference in BNP values between middle-aged and elderly patients (p2 = 0.05). The prevalence of FR was 54.8% in the elderly group, among elderly patients - 87.5%, centenarians - 100%. In the group of middle-aged people, the relationship was found between FR and the classification of NYHA (r = 0.59, p